SSRIs are a class of antidepressants that block the reabsorption (reuptake) of serotonin in the brain, increasing its availability in the synaptic cleft. Common SSRIs include fluoxetine (Prozac), sertraline (Zoloft), and citalopram (Celexa).
Key Points:
- Usage: First-line treatment for depression, generalized anxiety disorder, panic disorder, OCD, and various other conditions.
- Side Effects: Gastrointestinal upset, sexual dysfunction, headaches, insomnia or drowsiness. Generally less severe side effects than older antidepressants.
- Lag Time: May take several weeks to notice full therapeutic effects.
- Withdrawal: Stopping SSRIs abruptly can cause discontinuation symptoms; tapering is recommended.
