Wernicke’s Encephalopathy is an acute neurological condition caused by severe thiamine (vitamin B1) deficiency, often associated with chronic alcoholism. It’s characterized by confusion, oculomotor dysfunction, and ataxia.
Key Points:
- Symptoms (Classic Triad): Confusion, eye movement abnormalities (nystagmus, ophthalmoplegia), unsteady gait.
- Progression: If untreated, can lead to Korsakoff Syndrome (persistent memory problems) or death.
- Treatment: Immediate administration of thiamine; nutritional support; addressing alcohol misuse.
- Prevention: Adequate diet, monitoring thiamine levels in high-risk populations.
