Quetiapine (brand name Seroquel) is an atypical antipsychotic medication used primarily to treat schizophrenia, bipolar disorder, and in some cases, major depressive disorder (as an add-on). It helps balance certain neurotransmitters (dopamine and serotonin) in the brain.

Key Points:

  • Mechanism: Quetiapine blocks various receptor sites in the brain, influencing mood and perception.
  • Common Uses:
    • Schizophrenia: Reduces delusions, hallucinations, and disorganized thinking.
    • Bipolar Disorder: Manages manic episodes and can help stabilize mood; also indicated for bipolar depression.
    • Adjunctive in Depression: Sometimes prescribed when other antidepressants alone are insufficient.
  • Side Effects: May include sedation, weight gain, dizziness, and metabolic changes (e.g., elevated blood sugar or lipids). Regular monitoring is advised for long-term use.

Last Update: December 31, 2024